Gradient

Principals

Tom A. Lewandowski, Ph.D., DABT, ERT, ATS
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Education

Ph.D., Environmental Health/Toxicology, University of Washington

M.P.H., Environmental Chemistry, University of Michigan

B.S., Biology, University of Michigan

Diplomate of the American Board of Toxicology

Registered Toxicologist in Europe and the United Kingdom (ERT)

Fellow, Academy of Toxicological Sciences (ATS)

 

Expertise

  • Product Safety
  • Metals Toxicology
  • Pharmacokinetic Modeling
  • Risk Assessment
  • Alternative Assessment
  • Developmental Toxicology

Tom A. Lewandowski, Ph.D., DABT, ERT, ATS

Principal

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Dr. Lewandowski is a toxicologist and chemist working in Gradient's Seattle, Washington office.  He has over 25 years of experience in the areas of product safety evaluation, pharmacokinetics, metals toxicology, and developmental toxicology.  He is currently leading Gradient's efforts in the emerging area of green chemistry.  He is an affiliate faculty member at the University of Washington School of Public Health, where he lectures on toxicology and risk assessment.  In 2012-2013, he served as chair of the Society of Toxicology's Education Committee, which works to increase science literacy and public knowledge of toxicology.  He is an author of numerous book chapters and manuscripts relating to the practice of risk assessment, occupational health and consumer product toxicology.  He is a board certified in toxicology in the US as well as Europe.

Education

Ph.D., Environmental Health/Toxicology, University of Washington

M.P.H., Environmental Chemistry, University of Michigan

B.S., Biology, University of Michigan

Diplomate of the American Board of Toxicology

Registered Toxicologist in Europe and the United Kingdom (ERT)

Fellow, Academy of Toxicological Sciences (ATS)

 

Expertise

  • Product Safety
  • Metals Toxicology
  • Pharmacokinetic Modeling
  • Risk Assessment
  • Alternative Assessment
  • Developmental Toxicology

Services

Representative Projects

Worker and Consumer Risk Assessment: Evaluated potential health risks for production workers and consumers related to a plasticizer found in decorative films used during product assembly. Reviewed employee activity patterns related to installing the part, chemical-specific properties related to exposure and reproductive toxicity study data in animals for the chemical of interest and structural analogs.

Leather Product Alternatives Assessment: Evaluated potential alternatives to an antimicrobial chemical used in the production of leather that has significant skin sensitization potential. Conducted a literature review to identify feasible alternatives from the context of chemical hazard, availability, cost and performance.

Latex Residue Assessment: Identified an appropriate analytical testing strategy to confirm the presence of allergenic latex residue on a consumer product and assessed the risk of potential skin sensitization associated with expected consumer-level exposures. The evaluation helped the manufacturing company reach a decision about product safety.

Evaluation of Automotive Refrigerants: Conducted a risk assessment of two alternative chemicals proposed for use in vehicle air conditioning systems. Fault tree analysis (FTA) was used to estimate risks for vehicle occupants and repair personnel in the context of several different vehicle failure events (e.g., collisions and fires).

Alternatives Evaluation of Two Dielectric Fluids: Evaluated the relative risks posed by the use of acetonitrile or propylene glycol as a dielectric fluid in an electrical component of a consumer product. Considered exposures of consumers, assembly workers, and repair personnel in the event of product failure or damage.

Evaluation of Potential Allergenicity of Ingredients in a Medical Product: Assessed the ingredients contained in a medical diagnostic gel to determine their potential to produce skin sensitization or dermal irritation.

Risk Evaluation of Fungicides in Children’s Art Paint: Evaluated the potential health implications of a fungicidal contaminant in an art paint material. A rapid (24-hour) assessment was conducted and used by the client to decide on the need for a product recall.

Selected Publications

Lewandowski, TA; Cohen, JM.  2015. "Filling in the gaps: Approaches for dealing with missing health effects data." ABA Toxic Torts and Environmental Law Committee Newsl. : 1, 10-13.

Lewandowski, TA.  2014. "Green chemistry." In Encyclopedia of Toxicology (Third Edition): Volume 2. (Ed.: Wexler, P), Elsevier Inc., p471-472.

Rhomberg, LR; Goodman, JE; Lewandowski, TA.  2010. "Chapter 1.20: Risk assessment." Comprehensive Toxicology (Second Edition). Volume 1: General Principles. (Ed.: Bond, J), Elsevier Ltd., United Kingdom, p447-464.

Lewandowski, TA; Rhomberg, LR.  2009. "Dose response extrapolation for acute effects of toxic agents and its relevance to predict health risk related to disaster and terrorism associated events." Exposure and Risk Assessment of Chemical Pollution - Contemporary Methodology. Proceedings of the NATO Advanced Study Institute on Exposure and Risk Assessment of Chemical Pollution - Contemporary Methodology 1-10 July 2008 Sofia, Bulgaria. (Eds.: Simeonov, LI; Hassanien, MA), Springer

Lewandowski, TA; Bartell, SM; Yager, JW; Levin, L.  2009. "An evaluation of surrogate chemical exposure measures and autism prevalence in Texas." J. Toxicol. Environ. Health A 72 : 1592-1603.