Gradient

Principals

Tom A. Lewandowski, Ph.D., DABT, ERT, ATS
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Education

Ph.D., Environmental Health/Toxicology, University of Washington

M.P.H., Environmental Chemistry, University of Michigan

B.S., Biology, University of Michigan

Diplomate of the American Board of Toxicology

Registered Toxicologist in Europe and the United Kingdom (ERT)

Fellow, Academy of Toxicological Sciences (ATS)

 

Expertise

  • Product Safety
  • Metals Toxicology
  • Pharmacokinetic Modeling
  • Risk Assessment
  • Alternative Assessment
  • Developmental Toxicology

Tom A. Lewandowski, Ph.D., DABT, ERT, ATS

Principal

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Dr. Lewandowski is a toxicologist and chemist working in Gradient’s Seattle, Washington office.  He has over 30 years of experience in the areas of product safety evaluation, pharmacokinetics, metals toxicology, and developmental toxicology.  He is board certified as a toxicologist in both the US and Europe. He is an affiliate faculty member at the University of Washington School of Public Health where he lectures on toxicology and risk assessment. He is the author of numerous publications related to risk assessment methods (in particular the use of computer models).  He is a member of the OARS WEEL committee, which reviews toxicology data to develop workplace exposure guidelines for new chemical agents.

Education

Ph.D., Environmental Health/Toxicology, University of Washington

M.P.H., Environmental Chemistry, University of Michigan

B.S., Biology, University of Michigan

Diplomate of the American Board of Toxicology

Registered Toxicologist in Europe and the United Kingdom (ERT)

Fellow, Academy of Toxicological Sciences (ATS)

 

Expertise

  • Product Safety
  • Metals Toxicology
  • Pharmacokinetic Modeling
  • Risk Assessment
  • Alternative Assessment
  • Developmental Toxicology

Services

Representative Projects

Worker and Consumer Risk Assessment: Evaluated potential health risks for production workers and consumers related to a plasticizer found in decorative films used during product assembly. Reviewed employee activity patterns related to installing the part, chemical-specific properties related to exposure and reproductive toxicity study data in animals for the chemical of interest and structural analogs.

Leather Product Alternatives Assessment: Evaluated potential alternatives to an antimicrobial chemical used in the production of leather that has significant skin sensitization potential. Conducted a literature review to identify feasible alternatives from the context of chemical hazard, availability, cost and performance.

Latex Residue Assessment: Identified an appropriate analytical testing strategy to confirm the presence of allergenic latex residue on a consumer product and assessed the risk of potential skin sensitization associated with expected consumer-level exposures. The evaluation helped the manufacturing company reach a decision about product safety.

Evaluation of Automotive Refrigerants: Conducted a risk assessment of two alternative chemicals proposed for use in vehicle air conditioning systems. Fault tree analysis (FTA) was used to estimate risks for vehicle occupants and repair personnel in the context of several different vehicle failure events (e.g., collisions and fires).

Alternatives Evaluation of Two Dielectric Fluids: Evaluated the relative risks posed by the use of acetonitrile or propylene glycol as a dielectric fluid in an electrical component of a consumer product. Considered exposures of consumers, assembly workers, and repair personnel in the event of product failure or damage.

Evaluation of Potential Allergenicity of Ingredients in a Medical Product: Assessed the ingredients contained in a medical diagnostic gel to determine their potential to produce skin sensitization or dermal irritation.

Risk Evaluation of Fungicides in Children’s Art Paint: Evaluated the potential health implications of a fungicidal contaminant in an art paint material. A rapid (24-hour) assessment was conducted and used by the client to decide on the need for a product recall.

Selected Publications

Cohen, JM; Rice, JW; Lewandowski, TA.  2018. "Expanding the toolbox: Hazard-screening methods and tools for identifying safer chemicals in green product design." ACS Sustain. Chem. Eng. 6 : 1941-1950.

Cohen, JM; Lewandowski, TA.  2017. "Skin in the game: Potential skin hazards from consumer products." ABA Products Liability Litigation Newsl.

Lewandowski, T; Dodge, D.  2016. "Windows of susceptibility: Do OELs really protect workers from reproductive and developmental effects?" Syngergist (Akron) 27 : 22-25.

Lewandowski, TA.  2015. "Developmental toxicology." In Hamilton and Hardy's Industrial Toxicology (Sixth Edition). (Eds.: Harbison, RD; Bourgeois, MM; Johnson, GT), John Wiley & Sons, Inc., Hoboken, NJ, p1229-1240.

Lewandowski, TA.  2014. "Green chemistry." In Encyclopedia of Toxicology (Third Edition): Volume 2. (Ed.: Wexler, P), Elsevier Inc., p471-472.

Rhomberg, LR; Goodman, JE; Lewandowski, TA.  2010. "Chapter 1.20: Risk assessment." Comprehensive Toxicology (Second Edition). Volume 1: General Principles. (Ed.: Bond, J), Elsevier Ltd., United Kingdom, p447-464.

See All Tom Lewandowski Publications