Gradient

Recent Scientific Papers

In addition to the searchable list below, Gradient offers two of its own publications through the full website. Trends focuses on issues in environmental risk science and EH&S Nano News focuses on the latest in nanotechnology.


Showing Results for: "Cohen"

Cohen, J; Lewis, M. 2020

Risk assessment of extractables and leachables in medical devices.

Gradient Trends - Risk Science & Application 77:4.

Hansen, B; Marsh, C; Cohen, J. 2020

Defining the Edge: A Case Study in Expert Review of In Silico Hazard Predictions to Identify Activity Cliffs and Improve Chemical Risk Assessment.

Prepared for presentation to the Society of Toxicology (SOT) 59th Annual Meeting & ToxExpo, Anaheim, CA, March 15-19 (Conference cancelled)

Hansen, B; Marsh, C; Cohen, J. 2020

Defining the edge: A case study in expert review of in silico hazard predictions to identify activity cliffs and improve chemical risk assessment.

Prepared for presentation to the Society of Toxicology (SOT) 59th Annual Meeting & ToxExpo, Anaheim, CA, March 15-19 (Conference cancelled) Toxicologist 174:421.

Cohen, J. 2020

Predictive Toxicology Approaches for Medical Device Biocompatibility Assessment.

Presented at the 2020 SOT Virtual Meeting: Known Unknowns: Challenges and Approaches for Handling Chemical, Hazard, and Regulatory Uncertainty in Medical Device Safety Assessments

Cohen, J; Chang, RY. 2020

US FDA partial recognition of ISO 10993-18:2020 - Implications for toxicological risk assessment.

MDCPSS Newsl. 11:12-14.

American Society for Testing and Materials (ASTM), Subcommittee E55.03 on General Pharmaceutical Standards; Cohen, JM. 2020

Standard Guide for Derivation of Health-Based Exposure Limits (HBELs).

Yamada, T; Rhomberg, L; Haseman, JK; Greaves, P; Greim, H; Berry, C; Cohen, SM. 2019

Evaluation of the Potential Carcinogenicity of the Pyrethroid Imiprothrin in Mice.

Presented at the Society of Toxicology (SOT) 58th Annual Meeting, Baltimore, MD, March 10-14

Cohen, JM; Mattuck, R; Beck, BD. 2019

Physiologically Based Pharmacokinetic Modeling the Impacts of Intermittent Oral Exposures to Lead on Blood Lead Levels and Associated Health Risks.

Presented at the Society of Toxicology (SOT) 58th Annual Meeting, Baltimore, MD, March 10-14

Hansen, BC; Cohen, JM. 2019

Looking Under the Hood Expert Review of In Silico Carcinogenicity Predictions.

Presented at the Society of Toxicology (SOT) 58th Annual Meeting, Baltimore, MD, March 10-14

Yamada, T; Asano, K; Miyata, K; Rhomberg, LR; Haseman, JK; Greaves, P; Greim, H; Berry, C; Cohen, SM. 2019

Toxicological evaluation of carcinogenicity of the pyrethroid imiprothrin in rats and mice.

Regul. Toxicol. Pharmacol. 105:1-14.

Mattuck, R; Cohen, J. 2019

Evaluating safety of lead in food.

Gradient Trends - Risk Science & Application 75:1-2.

Cohen, JM; Rice, JW; Goodman, JE; Muehlberger, JP. 2019

Food Safety.

Presented at Gradient's Trends 75 Webinar

Cohen, JM; Liu, W; Jordi, M. 2019

Safety Evaluation of High Potency Mutagenic Impurities: A Timely Case Study.

Presented at the American College of Toxicology (ACT)'s 40th Annual Meeting, Phoenix, AZ, November 17-20

Cohen, J; Jordi, M; Rice, J. 2019

A Strategic Roadmap: Assessing Safety & Biocompatibility of Medical Devices.

Presented at Medmarc Medical Device Webinar

Cohen, JM; Rice, JW; Lewandowski, TA. 2018

Expanding the toolbox: Hazard-screening methods and tools for identifying safer chemicals in green product design.

ACS Sustain. Chem. Eng. 6:1941-1950.

Cohen, JM; Beltran-Huarac, J; Pyrgiotakis, G; Demokritou, P. 2018

Effective delivery of sonication energy to fast settling and agglomerating nanomaterial suspensions for cellular studies: Implications for stability, particle kinetics, dosimetry and toxicity.

NanoImpact 10:81-86.

Cohen, JM; Lewandowski, T. 2018

Predictive toxicology: Are we there yet?

Gradient Trends - Risk Science & Application 71:4-5.

Mohar, I; Cohen, JM; Pacheco Shubin, S; Lewandowski, TA. 2018

Skin Sensitization Assessment for 1,796 Chemicals Extracted from Consumer Apparel Products.

Presented at the Society of Toxicology (SOT) 57th Annual Meeting, San Antonio, TX, March 11-15

Rice, JW; Cohen, JM; Lewandowski, TA. 2018

Does one size fit all? Tailoring read-across methodology based on endpoint-specific criteria.

Presented at the 255th American Chemical Society (ACS) National Meeting & Exposition, New Orleans, LA

Cohen, JM; DeLoid, G; Pirela, SV; Beltran, J; Pyrgiotakis, G; Demokritou, P. 2018

A Standardized, Integrated Methodology across the ENM Dispersion Preparation-Colloidal Characterization-Cellular Dosimetry Continuum.

Presented at the Society of Toxicology (SOT) 57th Annual Meeting, San Antonio, TX

Cohen, JM. 2018

Predictive Toxicology: Are We There Yet?

Presented at the Defense Research Institute (DRI) Toxic Torts and Environmental Law Seminar, American Chemistry Council Member and Outside Counsel Meeting, Nashville, TN

Lunsman, TD; Cohen, JM; Goodman, JE; Park, JY. 2018

Pharmaceuticals.

Presented at Gradient's Trends 71 Webinar

Cohen, JM; Pacheco Shubin, S; Lewandowski, T. 2018

Predictive Toxicology Tools for Pharmaceutical Safety Evaluation.

Presented at the 2018 Applied Pharmaceutical Toxicology Conference, Boston, MA, May 15-17

Cohen, JM; Mohar, I; Lewandowski, T. 2018

Derivation of a PEL for Antibody Conjugated Iron Dextran Nanoparticles.

Presented at American College of Toxicology (ACT)'s 39th Annual Meeting, Palm Beach, FL, November 4-7

Rice, JW; Cohen, JM; Lewandowski, TA. 2018

Does one size fit all? Tailoring read-across methodology based on endpoint-specific criteria.

Presented at Navigating TSCA Reform: Evolving Chemical Hazard Evaluation Strategies for SMEs (Session Two) Webinar

Petito Boyce, C; Sax, SN; Cohen, JM. 2017

Particle size distributions of lead measured in battery manufacturing and secondary smelter facilities and implications in setting workplace lead exposure limits.

J. Occup. Environ. Hyg. 14:594-608.

DeLoid, GM; Cohen, JM; Pyrgiotakis, G; Demokritou, P. 2017

Preparation, characterization, and in vitro dosimetry of dispersed, engineered nanomaterials.

Nat. Protoc. 12:355-371.

Cohen, JM; Lewandowski, T. 2017

Alternative Methods for Skin Sensitization Quantitative Risk Assessment.

Presented at the Society of Toxicology (SOT) 56th Annual Meeting, Baltimore, MD, March 12-16

Cook, TJ; Cohen, JM; Lewandowski, TA. 2017

Evaluation of Health Risks Associated with Low-Frequency Environmental Ultrasound Exposure and the Potential for Electronic Medical Device Interference.

Presented at the Society of Toxicology (SOT) 56th Annual Meeting, Baltimore, MD, March 12-16

Lewandowski, TA; Cohen, JM. 2017

Nickel and Trivalent Chromium Thresholds for Skin Sensitization.

Presented at the Society of Toxicology (SOT) 56th Annual Meeting, Baltimore, MD, March 12-16

Lewandowski, TA; Skall, DG; Reid, KR; Cohen, JM. 2017

Alternative Assessment and Hazard Evaluation Approaches for Emerging Environmental Concerns: A Case Study of Refrigerants in Domestic Refrigerators.

Presented at the Society for Risk Analysis (SRA) Policy Forum: Risk Governance for Key Enabling Technologies, Venice, Italy, March 1-3

Marsh, CM; Butler, CH; Cohen, JM. 2017

Improving Read-Across for GHS Hazard Classification Using ECHA's Read-Across Assessment Framework (RAAF): Alkylbenzenes and Skin Sensitization.

Presented at the Society for Chemical Hazard Communication (SCHC) Spring 2017 Meeting, New Orleans, LA, March 25-29

Cohen, JM; DeLoid, G; Pirela, SV; Beltran, J; Pyrgiotakis, G; Demokritou, P. 2017

An Integrated Methodology Across the Dispersion Preparation-Characterization-In vitro Dosimetry Continuum for Engineered Nanomaterials.

Presented at the Nanotech 2017 Conference & Expo, Washington, DC, May 14-17

Cohen, J. 2017

Nanomaterials in Food and Food Contact Substances: Hazards, Risks and Regulation.

Presented at the Nanotech 2017 Conference & Expo, Washington, DC, May 14-17

Cohen, JM; Lewandowski, TA. 2017

Skin in the game: Potential skin hazards from consumer products.

ABA Products Liability Litigation Newsl.

Cohen, JM; Pacheco Shubin, S; Lewandowski, T. 2017

Hazard Screening Approaches for Identifying Safer Chemicals.

Presented at the ACS 21st Annual Green Chemistry & Engineering Conference, Reston, VA

Lewandowski, T; Cohen, JM. 2017

Expert Review of In Silico Predictions for Skin Sensitization Potency.

Presented at the Tenth World Congress on Alternatives and Animal Use in the Life Sciences (WC10), Seattle, WA, August 20-24

Pacheco Shubin, S; Cohen, JM; Dodge, DG; Lewandowski, T. 2017

Hazard Screening Approaches for Identifying Developmental and Reproductive Toxicity in the Workplace.

Presented at the Teratology Society 57th Annual Meeting, Denver, CO, June 24-28

Lewandowski, T; Cohen, JM. 2017

Expert Review of In Silico Predictions for Skin Sensitization Potency.

Presented at American College of Toxicology (ACT)'s 38th Annual Meeting, Palm Springs, CA, November 5-8

Lewandowski, T; Cohen, JM. 2016

Surrogate Evaluation and Read Across for Hazard Assessment: Best Practices and Potential Pitfalls.

Presented at the Society of Toxicology (SOT) 55th Annual Meeting, New Orleans, LA, March 13-17

Prueitt, RL; Cohen, JM; Goodman, JE. 2016

Evaluation of Atherosclerosis as a Mode of Action for the Cardiovascular Effects of Particulate Matter.

Presented at the Society of Toxicology (SOT) 55th Annual Meeting, New Orleans, LA, March 13-17

Cohen, JM; Rice, JW; Lewandowski, T. 2016

What's in Your Toolbox? Methods and Tools for Alternative Assessments with Data-Poor Chemicals.

Presented at the ACS 20th Annual Green Chemistry & Engineering Conference, Portland, OR, June 14-16

Cohen, JM. 2016

Nanobombs protect consumers from foodborne microorganisms.

Food Saf. 22:22, 24-25, 62.

Lewandowski, TA; Cohen, JM. 2016

Skin sensitization risk assessment: Considering available data for weight of evidence assessments (Letter).

Regul. Toxicol. Pharmacol.

Lynch, HN; Loftus, CT; Cohen, JM; Kerper, LE; Kennedy, EM; Goodman, JE. 2016

Weight-of-evidence evaluation of associations between particulate matter exposure and biomarkers of lung cancer.

Regul. Toxicol. Pharmacol. 82:53-93.

Skall, DG; Reid, KR; Cohen, JM; Lewandowski, TA. 2016

IC2 Level 1 Alternative Assessment for Refrigerants in Domestic Refrigerators.

Presented at SETAC North America 37th Annual Meeting, Orlando, FL, November 6-10

Rice, JW; Cohen, JM; Lewandowski, TA. 2016

Building Your Toolbox: Read-Across Tools for Alternatives Assessment.

Presented at SETAC North America 37th Annual Meeting/7th SETAC World Congress, Orlando, FL

Cohen, J. 2016

Nanoscale Substances in Food: Small Materials Raise Big Questions.

Presented at the Society for Risk Analysis (SRA) Annual Meeting, San Diego, CA

Cohen, J; Lewandowski, T. 2016

Alternatives assessment: On the hunt for safer chemicals.

Gradient Trends - Risk Science & Application 66:3-4.

Cohen, JM; Demokritou, P. 2015

Dosimetry for in vitro nanotoxicology: Too complicated to consider, too important to ignore.

In Nanoparticles in the Lung: Environmental Exposure and Drug Delivery. (Eds.: Tsuda, A; Gehr, P), CRC Press, Boca Raton, FL.