Gradient

Recent Scientific Papers

In addition to the searchable list below, Gradient offers two of its own publications through the full website. Trends focuses on issues in environmental risk science and EH&S Nano News focuses on the latest in nanotechnology.


Showing Results for: "Rhomberg"

Prueitt, RL; Goodman, JE; Rhomberg, LR. 2013

Hypothesis-Based Weight-of-Evidence Evaluation of the Human Carcinogenicity of Toluene Diisocyanate.

Presented at the Society of Toxicology (SOT) 52nd Annual Meeting, San Antonio, TX, March 10-14

Goodman, JE; Prueitt, RL; Rhomberg, LR. 2013

Hypothesis-Based Weight-of-Evidence Evaluation of the Human Carcinogenicity of Toluene Diisocyanate.

Presented at the Conference on Isocyanates and Health: Past, Present and Future

Goodman, JE; Prueitt, RL; Rhomberg, LR. 2013

Incorporating low-dose epidemiology data in a chlorpyrifos risk assessment.

Dose Response 11:207-219.

Rhomberg, LR; Goodman, JE; Bailey, LA; Prueitt, RL; Beck, NB; Bevan, C; Honeycutt, M; Kaminski, NE; Paoli, G; Pottenger, LH; Scherer, RW; Wise, KC; Becker, RA. 2013

A survey of frameworks for best practices in weight-of-evidence analyses.

Crit. Rev. Toxicol. 43:753-784.

Prueitt, RL; Rhomberg, LR; Goodman, JE. 2013

Hypothesis-based weight-of-evidence evaluation of the human carcinogenicity of toluene diisocyanate.

Crit. Rev. Toxicol. 43:391-435.

Goodman, JE; Prueitt, RL; Sax, SN; Bailey, LA; Rhomberg, LR. 2013

Evaluation of the causal framework used for setting National Ambient Air Quality Standards.

Crit. Rev. Toxicol. 43:829-849.

Pemberton, M; Bailey, LA; Rhomberg, LR. 2013

Hypothesis-based weight-of-evidence evaluation of methyl methacrylate olfactory effects in humans and derivation of an occupational exposure level.

Regul. Toxicol. Pharmacol. 66:217-233.

Rhomberg, L; Bailey, EA; Nascarella, MA. 2013

Hypothesis-Based Weight-of-Evidence (HBWoE) and Dose-Response Evaluation for Naphthalene Carcinogenicity.

Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 11

Rhomberg, L; Bailey, EA. 2013

Hypothesis-Based Weight-of-Evidence: An Approach to Assessing Causation and its Application to Regulatory Toxicology.

Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 9

Rhomberg, L. 2013

New, diverging short-term limits for TCE vapors.

Gradient Trends - Risk Science & Application 57:3,5.

Rhomberg, LR. 2013

Using Existing Study Data or Methodologies from Epidemiology and Toxicology to Evaluate Diverse Stressors.

Presented at the T4-B.4: Session on Cumulative Risk Assessment Symposium, Society for Risk Analysis Annual Meeting, San Francisco, CA

Bailey, LA; Prueitt, RL; Rhomberg, LR. 2012

Hypothesis-based weight-of-evidence evaluation of methanol as a human carcinogen.

Regul. Toxicol. Pharmacol. 62:278-291.

Goodman, JE; Rhomberg, LR; Prueitt, RL. 2012

Why styrene should not be classified as a human carcinogen and does not belong in the NTP's 12th Report on Carcinogens.

Chem. Regulation Rep. 36:311-314.

Prueitt, RL; Goodman, JE; Bailey, LA; Rhomberg, LR. 2012

Hypothesis-Based Weight-of-Evidence Evaluation of the Neurodevelopmental Effects of Chlorpyrifos.

Presented at the Society of Toxicology (SOT) 51st Annual Meeting, San Francisco, CA, March 11-15

Rhomberg, LR; Goodman, JE; Foster, WG; Borgert, CJ; Van Der Kraak, G. 2012

A critique of the European Commission Document, State of the Art Assessment of Endocrine Disrupters.

Crit. Rev. Toxicol. 42:465-473.

Rhomberg, LR; Goodman, JE. 2012

Low-dose effects and nonmonotonic doseresponses of endocrine disrupting chemicals: Has the case been made?

Regul. Toxicol. Pharmacol. 64:130-133.

Rhomberg, LR; Goodman, JE; Foster, WG; Borgert, CJ; Van Der Kraak, G. 2012

Response to Kortenkamp et al. rebuttal.

Crit. Rev. Toxicol. 42:790-791.

Rhomberg, LR. 2012

Weight-of-Evidence Frameworks, Systems, and Tools: A Survey of Existing Approaches Evaluations.

Presented at the Putting it All Together: Recent Developments in Risk Assessment Approaches Symposium, Society for Risk Analysis Annual Meeting, San Francisco

Rhomberg, LR; Goodman, JE; Haber, LT; Dourson, M; Andersen, ME; Klaunig, JE; Meek, B; Price, PS; McClellan, RO; Cohen, SM. 2011

Linear low-dose extrapolation for noncancer health effects is the exception, not the rule.

Crit. Rev. Toxicol. 41:1-19.

Rhomberg, LR; Bailey, LA; Goodman, JE; Hamade, A; Mayfield, D. 2011

Is exposure to formaldehyde in air causally associated with leukemia? - A hypothesis-based weight-of-evidence analysis.

Crit. Rev. Toxicol. 41:555-621.

Bailey, L; Hamade, AK; Rhomberg, LR. 2011

Weight-of-Evidence Evaluation of a Plausible Mode of Action for Leukemogenesis from Inhalation Exposure to Formaldehyde.

Presented at the Society of Toxicology (SOT) 50th Annual Meeting, Washington, DC, March 6-11

Goodman, JE; Mayfield, DB; Bailey, L; Rhomberg, LR. 2011

Weight-of-Evidence Evaluation of Formaldehyde Exposure and Leukemia Risk.

Presented at the Society of Toxicology (SOT) 50th Annual Meeting, Washington, DC

Hamade, AK; Bailey, L; Rhomberg, LR. 2011

Does Formaldehyde Cause Hematotoxicity? A Weight-of-Evidence Evaluation of Hematotoxicity Studies in Humans and Animals in the Context of Leukemogenicity.

Presented at the Society of Toxicology (SOT) 50th Annual Meeting, Washington, DC

Rhomberg, LR. 2011

Interpreting dose-response information on intermediate stages of causal cascades in toxicity mode of action.

Presented at the Society of Toxicology (SOT) 50th Annual Meeting, Washington, DC

Rhomberg, LR. 2011

Practical risk assessment and management issues arising were we to adopt low-dose linearity for all endpoints.

Dose Response 9:144-157.

Prueitt, RL; Goodman, JE; Bailey, LA; Rhomberg, LR. 2011

Hypothesis-based weight-of-evidence evaluation of the neurodevelopmental effects of chlorpyrifos.

Crit. Rev. Toxicol. 41:822-903.

Bailey, LA; Goodman, JE; Rhomberg, LR. 2011

Hypothesis-based Weight-of-Evidence Evaluation of Naphthalene: Carcinogenic Hazard Assessment and Mode of Action.

Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 32nd Annual Meeting, Boston, MA, November 14.

Rhomberg, LR. 2011

Comparison of Strategies to Structure Weight-of-Evidence Evaluations.

Presented at the "Synthesizing Evidence for Evidence-Based Decisionmaking: Part 1" Workshop, Society for Risk Analysis Annual Meeting, Charleston, SC, December 5.

Rhomberg, LR. 2011

Overview of Approaches for Evidence-Based Decisionmaking.

Presented at the "Synthesizing Evidence: An Introduction to Systematic Reviews,Meta-Analysis, and Expert Elicitation" Workshop, Society for Risk Analysis Annual Meeting, Charleston, SC, December 4.

Rhomberg, LR; Chandalia, JK; Long, CM; Goodman, JE. 2011

Measurement error in environmental epidemiology and the shape of exposure-response curves.

Crit. Rev. Toxicol. 41:651-671.

Rhomberg, LR. 2011

Thoughts on EPA and Emerging Science: A Personal Perspective.

Presented at Duke Environmental Law & Policy Forum: The EPA at 40

Rhomberg, LR. 2011

Weight of Evidence Frameworks in the Regulatory Context: A Conceptual Comparison.

Presented at the "Solving the Weight of Evidence Problem: A Way Forward?" Symposium, AAAS Annual Meeting, Washington, DC, February 18

Beyer, LA; Rhomberg, LR; Hamade, AK; Beck, B. 2010

Evaluation of Recent Information on Carcinogenicity of Perchloroethylene (PCE) in Humans.

Presented at the Society of Toxicology (SOT) 49th Annual Meeting, Salt Lake City, UT

Rhomberg, LR. 2010

Hypothesis-based approaches to weighing information of complex datasets.

Presented at the Society of Toxicology (SOT) 49th Annual Meeting, Salt Lake City, UT

Rhomberg, LR. 2010

Noncancer toxicity potential at low doses: Background considered statistically and biologically.

Presented at the Society of Toxicology (SOT) 49th Annual Meeting, Salt Lake City, UT

Kerper, LE; Goodman, JE; Petito Boyce, C; Prueitt, RL; Rhomberg, LR. 2010

Weight-of-Evidence Analysis of Exposures to Dioxins and Dioxin-like Compounds and Associations with Thyroid Hormone Levels During Early Development.

Presented at the Society of Toxicology (SOT) 49th Annual Meeting, Salt Lake City, UT

Rhomberg, LR; Goodman, JE; Lewandowski, TA. 2010

Chapter 1.20: Risk assessment.

Comprehensive Toxicology (Second Edition). Volume 1: General Principles. (Ed.: Bond, J), Elsevier Ltd., United Kingdom

Goodman, JE; Kerper, LE; Petito Boyce, C; Prueitt, RL; Rhomberg, LR. 2010

Weight-of-evidence analysis of human exposures to dioxins and dioxin-like compounds and associations with thyroid hormone levels during early development.

Regul. Toxicol. Pharmacol. 58:79-99.

Rhomberg, LR. 2010

Toxicity testing in the 21st century: How will it affect risk assessment?

J. Toxicol. Environ. Health B 13:361-375.

Rhomberg, LR; Bailey, LA; Goodman, JE. 2010

Hypothesis-based weight of evidence: A tool for evaluating and communicating uncertainties and inconsistencies in the large body of evidence in proposing a carcinogenic mode of action - Naphthalene as an example.

Crit. Rev. Toxicol. 40:671-696.

Goodman, J; Rhomberg, L. 2010

Current controversies in non-cancer dose-response.

Gradient Trends - Risk Science & Application 49:1-2.

Rhomberg, L; Bailey, L. 2010

Weigh the evidence! But how much does evidence weigh?

Gradient Trends - Risk Science & Application 49:4.

Rhomberg, LR; Goodman, JE; Lewandowski, TA. 2010

Risk assessment.

Comprehensive Toxicology (Second Edition). Volume 1: General Principles. (Editor: McQueen, CA), Elsevier Ltd. (United Kingdom)

Goodman, JE; Witorsch, RJ; McConnell, EE; Sipes, IG; Slayton, TM; Yu, CJ; Franz, AM; Rhomberg, LR. 2009

Weight-of-evidence evaluation of reproductive and developmental effects of low doses of bisphenol A.

Crit. Rev. Toxicol. 39:1-75.

Rhomberg, LR. 2009

Risk assessment in the 21st Century: Changes wrought by changing science.

Risk Anal. 29:488-489.

Bailey, L; Rhomberg, L. 2009

Hypothesis-based weight-of-evidence (HBWOE) - A tool for evaluating the entire body of literature in considering human relevance and potential carcinogenic mode of action - Naphthalene as an example.

Presented at the Society of Toxicology (SOT) 48th Annual Meeting, Baltimore, MD, March 15-19

Goodman, JE; Rhomberg, LR. 2009

A Weight-of-Evidence Approach to Evaluating Epidemiological Data on Styrene Cancer Hazards.

Presented at the Society of Toxicology (SOT) 48th Annual Meeting, Baltimore, MD, March 15-19

Lewandowski, TA; Rhomberg, LR. 2009

Dose response extrapolation for acute effects of toxic agents and its relevance to predict health risk related to disaster and terrorism associated events.

Exposure and Risk Assessment of Chemical Pollution - Contemporary Methodology. Proceedings of the NATO Advanced Study Institute on Exposure and Risk Assessment of Chemical Pollution - Contemporary Methodology 1-10 July 2008 Sofia, Bulgaria. (Eds.: Simeonov, LI; Hassanien, MA), Springer

Goodman, JE; Rhomberg, LR. 2009

Bisphenol A.

In Endocrine-Disrupting Chemicals in Food. (Ed.: Shaw, I), Woodhead Publishing Ltd, Cambridge, UK

Rhomberg, LR. 2009

Epi/tox perspective on Chapter 2: What data sets per se say.

Uncertainty Modeling in Dose Response. (Ed: Cooke, R), John Wiley & Sons, Inc., Hoboken, New Jersey