Gradient

Recent Scientific Papers

In addition to the searchable list below, Gradient offers two of its own publications through the full website. Trends focuses on issues in environmental risk science and EH&S Nano News focuses on the latest in nanotechnology.


Showing Results for: "Rhomberg"

Rhomberg, LR. 2009

Epi/tox perspective on Chapter 2: What data sets per se say.

Uncertainty Modeling in Dose Response. (Ed: Cooke, R), John Wiley & Sons, Inc., Hoboken, New Jersey

Rhomberg, LR. 2009

Uptake kinetics, species differences, and the determination of equivalent combinations of air concentration and exposure duration for assessment of acute inhalation toxicity.

Hum. Ecol. Risk Assess. 15:1099-1145.

Bailey, L; Rhomberg, L. 2009

Hypothesis-Based Weight-of-Evidence (HBWOE) Evaluation of Naphthalene - Carcinogenic Hazard Assessment and Mode of Action.

Society for Risk Analysis Annual Meeting, Baltimore, MD, December 6-9, 2009

Goodman, JE; Gaylor, D; Beyer, LA; Rhomberg, LR; Beck, BD. 2008

Effects of MTBE on the reported incidence of Leydig cell tumors in SpragueDawley rats: Range of possible Poly-3 results.

Regul. Toxicol. Pharmacol. 50:273-284.

Dodge, DG; Haber, LT; Kopras, E; Goodman, JE; Pagan, I; Gift, JS; Rhomberg, LR. 2008

Case Studies for the Development of a Pathophysiological Progression Model.

Presented at the Society of Toxicology (SOT) 47th Annual Meeting, Seattle, WA, March 16-20

Dodge, DG; Zhao, QJ; Haber, LT; Goodman, JE; Pagan, I; Foureman, GL; Rhomberg, LR. 2008

Case Studies for the Development of a Pathophysiological Progression Model: Fatty Liver.

Society for Risk Analysis Annual Meeting, San Antonio, TX, December 9-12

Rhomberg, LR. 2008

Acute Inhalation Toxicity: Physiological Time and Species-Specific Half-Life as Determinants of Animal-to-Human Extrapolation of Toxicological Equivalent Combinations of Air Concentrations and Duration.

Presented at the Society of Toxicology (SOT) 47th Annual Meeting, Seattle, WA, March 16-20

Rhomberg, LR; Goodman, JE. 2008

CERHR conclusions would have been strengthened by a more explicit weight-of-evidence analysis.

Birth Defects Res. B Dev. Reprod. Toxicol. 83:155-156.

Aylward, LL; Goodman, JE; Charnley, G; Rhomberg, LR. 2008

A margin of exposure approach to assessment of non-cancer risks of dioxins based on human exposure and response data.

Environ. Health Perspect. 116:13441351.

Rhomberg, LR; Goodman, JE; McConnell, EE; Sipes, IG; Witorsch, RJ; Slayton, TM; Yu, CJ; Lewis, AS. 2007

An Updated Weight of the Evidence Evaluation of Reproductive and Developmental Effects of Low Doses of Bisphenol A.

Presented at the Society of Toxicology (SOT) 46th Annual Meeting, Charlotte, NC, March 25-29

Goodman, JE; Gaylor, D; Beyer, LA; Rhomberg, LR; Beck, BD. 2007

MTBE Is Not Associated with a Statistically Significant Increase in Leydig Cell Tumors in Sprague-Dawley Rats.

Presented at the Society of Toxicology (SOT) 46th Annual Meeting, Charlotte, NC, March 25-29

Rhomberg, LR; Baetcke, K; Blancato, J; Bus, J; Cohen, S; Conolly, R; Dixit, R; Doe, J; Ekelman, K; Fenner-Crisp, P; Harvey, P; Hattis, D; Jacobs, A; Jacobson-Kram, D; Lewandowsky, T; Liteplo, R; Pelkonen, O; rice, J; Somers, D; Turturro, A; West, W; Olin, S. 2007

Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: Approaches to dose selection.

Crit. Rev. Toxicol. 37:729-837.

Haber, LT; Kopras, EJ; Goodman, JE; Dodge, DG; Rhomberg, LR; Pagan, I. 2007

Case Studies for the Development of a Pathophysiological Progression Model: Phosgene-Induced Lung Fibrosis.

Society for Risk Analysis Annual Meeting

Pagan, I; Haber, LT; Rhomberg, LR; Goodman, JE; Dodge, DG; Foureman, GL. 2007

Development of a Pathophysiological Progression Model for Selected Endpoints.

Society for Risk Analysis Annual Meeting

Goodman, JE; McConnell, EE; Sipes, IG; Witorsch, RJ; Slayton, TM; Yu, CJ; Lewis, AS; Rhomberg, LR. 2006

An updated weight of the evidence evaluation of reproductive and developmental effects of low doses of bisphenol A.

Crit. Rev. Toxicol. 36:387-457.

Rhomberg, LR; Lewandowski, TA. 2006

Methods for identifying a default cross-species scaling factor.

Hum. Ecol. Risk Assess. 12:1094-1127.

Lewandowski, TA; Rhomberg, LR. 2005

A proposed methodology for selecting a trichloroethylene inhalation unit risk value for use in risk assessment.

Regul. Toxicol. Pharmacol. 41:39-54.

Rhomberg, LR. 2005

Seeking optimal design for animal bioassay studies.

Toxicol. Sci. 84:1-3.

Gray, GM; Baskin, SI; Charnley, G; Cohen, JT; Gold, LS; Kerkvliet, NI; Koenig, HM; Lewis, SC; McClain, RM; Rhomberg, LR; Snyder, JW; Weekley, LB. 2005

The Annapolis Accords on the Use of Toxicology in Risk Assessment and Decision-Making.

Lewandowski, TA; Beyer, LA; Rhomberg, LR; Beck, BD. 2005

A historical perspective on long term animal bioassays.

Presented at the Society of Toxicology (SOT) 44th Annual Meeting, New Orleans, LA, March 6-10

Rhomberg, L; Seeley, M. 2005

Environmental hormone disruptors.

In Encyclopedia of Toxicology (Second Edition). (Ed.: Wexler, P), Elsevier Press, San Diego, CA

Rhomberg, LR. 2004

Separating pharmacokinetic and pharmacodynamic components in empirical adjustment factor distributions.

Hum. Ecol. Risk Assess. 10:79-90.

Gray, GM; Cohen, JT; Cunha, G; Hughes, C; McConnell, EE; Rhomberg, L; Sipes, IG; Mattison, D. 2004

Weight of the evidence evaluation of low-dose reproductive and developmental effects of bisphenol A.

Hum. Ecol. Risk Assess. 10:875-921.

Rhomberg, LR. 2004

Mechanistic considerations in the harmonization of dose-response methodology: The role of redundancy at different levels of biological organization.

Risk Analysis and Society: An Interdisciplinary Characterization of the Field. (Eds.: McDaniels, T; Small, MJ), Cambridge University Press, Cambridge, UK.

Wells, CS; Rhomberg, LR; Lewandowski, TA. 2003

Tumor incidence in humans and rodents: Efforts to reconcile the observed data with BBDR model predictions.

Presented at the Society of Toxicology (SOT) 42nd Annual Meeting, Salt Lake City, UT, March 9-13

Rhomberg, LR. 2002

It's time for risk assessment to step up to the challenge of informing benefits analysis.

Risk Policy Rep. :35-37.

Cohen, JT; Carlson, G; Charnley, G; Coggon, D; Delzell, E; Graham, JD; Greim, H; Krewski, D; Medinsky, M; Monson, R; Paustenbach, D; Petersen, B; Rappaport, S; Rhomberg, L; Ryan, PB; Thompson, K. 2002

A comprehensive evaluation of the potential health risks associated with occupational and environmental exposure to styrene.

J. Toxicol. Environ. Health B Crit. Rev. 5:1-263.

Brand, KP; Catalano, PJ; Hammitt, JK; Rhomberg, L; Evans, JS. 2002

Limitations to empirical extrapolation studies: The case of BMD ratios.

Risk Anal. 21:625-640.

Rhomberg, LR. 2002

Dose scaling and extrapolation across age groups.

Hum. Ecol. Risk Assess. 8:783-803.

Crettaz, P; Pennington, D; Rhomberg, L; Brand, K; Jolliet, O. 2002

Assessing human health response in life cycle assessment using ED10s and DALYs: Part 1 - Cancer effects.

Risk Anal. 22:931-945.

Pennington, D; Crettaz, P; Tauxe, A; Rhomberg, L; Brand, K; Jolliet, O. 2002

Assessing human health response in life cycle assessment using ED10s and DALYs: Part 2 - Noncancer effects.

Risk Anal. 22:947-963.

Kuo, J; Linkov, I; Rhomberg, L; Polkanov, M; Gray, G; Wilson, R. 2002

Absolute risk or relative risk? A study of intraspecies and interspecies extrapolation of chemical-induced cancer risk.

Risk Anal. 22:141-157.

Lewandowski, TA; Wells, C; Rhomberg, LR. 2002

Interspecies differences in BBDR model input parameters and their implication for modeling tumor incidence.

Presented at the Society of Toxicology (SOT) 41st Annual Meeting, Nashville, TN, March 17-21

Rhomberg, LR; Baird, S; Evans, J; Williams, P; Wilson, A. 2002

Quantifying uncertainty in human reproductive risk projected from rat inhalation studies on ethylene oxide: A framework basod on data-based statistical distributions of extrapolation factors.

Presented at the Society of Toxicology (SOT) 41st Annual Meeting, Nashville, TN, March 17-21

Evans, JS; Rhomberg, LR; Williams, PL; Wilson, AM; Baird, SJS. 2001

Reproductive and developmental risks from ethylene oxide: A probabilistic characterization of possible regulatory thresholds.

Risk Anal. 21:697-717.

Rhomberg, LR. 2000

Dose-response analyses of the carcinogenic effects of trichloroethylene in experimental animals.

Environ. Health Perspect. 108:343-358.

Rhomberg, LR. 2000

Risk characterization of the potential for human health impact from environmental concentrations of endocrine modulators.

Nutrition 16:551-554.

Rhomberg, LR. 2000

Mode of action as a guide to quantitative analytical approaches.

Presented at the Society of Toxicology (SOT) 39th Annual Meeting, Philadelphia, PA, March 21

National Research Council; Rhomberg, LR. 2000

Strategies to Protect the Health of Deployed U.S. Forces: Analytical Framework for Assessing Risks.