Select Projects

Regulatory Comment:  Evaluated US EPA’s draft 2023 Integrated Science Assessment (ISA) and Integrated Review Plan (IRP) for the National Ambient Air Quality Standards (NAAQS) for Lead (Pb) as part of its review for the NAAQS.

Causation Analysis:  Conducted a general causation analysis regarding the impacts of inorganic arsenic, lead, and methylmercury exposure on intelligence and behavior using toxicology and epidemiology studies.

Causation Analysis:  Conducted an in-depth review of epidemiology studies on the pulmonary health effects, including pneumoconiosis, lung function, and respiratory symptoms, of bauxite and alumina dust inhalation in occupational settings.

Hazard Assessment of Sunscreen Ingredients:  Assessed various sunscreen ingredients using Globally Harmonized System of Classification and Labelling of Chemicals (GHS) criteria, with particular focus on carcinogenicity, reproductive and developmental toxicity, respiratory sensitization, repeated toxicity, and endocrine-disrupting endpoints.

Inhalation Toxicity Assessment:  Performed an in-depth review and analysis of epidemiology and exposure studies of bleach-based cleaners (as well as unintended mixtures of cleaners) to determine the acute toxicity of cleaning-fume inhalation.

Biokinetic Modeling:  Performed lead modeling to estimate the extent to which blood lead levels would decrease following the removal of lead sources in a residence.

Selected Publications

Park, HR; Azzara, D; Cohen, ED; Boomhower, SR; Diwadkar, AR; Himes, BE; O’Reilly, MA; Lu, Q. 2024. “Identification of novel NRF2-dependent genes as regulators of lead and arsenic toxicity in neural progenitor cells.” J. Hazard. Mater. 463:132906.

Boomhower, SR. 2022. “Public health issues of legalizing cannabis: Considerations for future studies.” In Handbook of Substance Misuse and Addictions: From Biology to Public Health. (Eds.: Patel, VB; Preedy, VR) Springer, Cham, Switzerland, p1-18.

Bailey, LA; Boomhower, SR. 2021. “Potential implications of new information concerning manganese Ohio community health effects studies.” Regul. Toxicol. Pharmacol. 127:105069.

Boomhower, SR; Long, CM; Li, W; Manidis, TD; Bhatia, A; Goodman, JE. 2021. “A review and analysis of personal and ambient PM2.5 measurements: Implications for epidemiology studies.” Environ. Res. 204:112019.

Johnson, KR; Boomhower, SR; Newland, MC. 2019. “Behavioral effects of chronic WIN 55,212-2 administration during adolescence and adulthood in mice.” Exp. Clin. Psychopharmacol. 27:348-358.

Boomhower, SR; Newland, MC. 2019. “D-amphetamine and methylmercury exposure during adolescence alters sensitivity to monoamine uptake inhibitors in adult mice.” Neurotoxicology 72:61-73.

Boomhower, SR; Newland, MC. 2019. “Adolescent methylmercury exposure: Behavioral mechanisms and effects of sodium butyrate in mice.” Neurotoxicology 70:33-40.