In legal cases involving health claims and chemical exposure from consumer or other manufactured products, clients engage Gradient because of our in-depth chemical-specific knowledge, technically sound quantitative analysis, and strong track record of providing scientifically credible testimony in understandable terms. Our specialized knowledge and extensive research resources frequently play pivotal roles in these cases. Areas of particular expertise that we offer include toxicological and epidemiological causation, dose reconstruction (including historical), alternative chemical effects, chemical source identification, historical knowledge of toxicology, and disease cluster evaluation.
Evaluation of Chemical in Children’s Toy
Gradient assessed whether a toxicological evaluation of a toy was sufficient for determining children’s health risks. We analyzed potential routes of exposure to and toxicity of a chemical found in the toy, as well as evidence that such exposure could have resulted in neurodevelopmental effects in a particular individual.
Weight of Evidence Causation Evaluation
Gradient has performed causation evaluations for a variety of different chemicals in a legal context. These evaluations typically consider evidence from a variety of different lines of evidence, often including animal toxicology, epidemiology, exposure, and mechanism of action studies. Examples of chemicals that Gradient has evaluated in this fashion include bisphenol-A, methanol, trichloroethylene, diesel exhuase, asbestos, talc, and others.
Product Recall Case Involving Plastic Mug Inserts
Gradient assessed potential exposures to chemicals leaching from plastic mug inserts and advised the client on the scientific merits of a product recall.
Product Recall Case Involving Plastic Mug Inserts
Gradient assessed potential exposures to chemicals leaching from plastic mug inserts and advised the client on the scientific merits of a product recall.
Assessment of Side Effects of Pharmaceutical Agent
Gradient conducted a peer review of published scientific literature, including epidemiology studies, to assess whether side effects could have been anticipated from existing studies.
Evaluation of Steroid Adulteration Claims in Dietary Supplement
In separate lawsuits brought by an NFL player and an Olympic athlete, Gradient designed and conducted a forensic testing program to determine the presence and source of anabolic steroids in a dietary supplement.
