Winter 2026

What’s New at Gradient

Awards and Announcements

 

Lindsey Borton, Cassandra Meakin, Nicole Olgun, and Katie Roach are now Diplomates of the American Board of Toxicology (DABT).

Joel Cohen has been accepted as a Fellow of the Academy of Toxicological Sciences (ATS).

Publications

 

Berg, P; Hebert, RM; McKenzie, MA; Groff, LD; Wiman, C; Garneau, P; Gould, J; Kuzminski, S; McGlathery, KJ; Muñoz, S; Hughes, AR; Stubbins, A; Miller, LE. 2025. “Century-scale resilience of stored seagrass blue carbon.” Limnol. Oceanogr. Lett. 10(6):990-998. doi.: 10.1002/lol2.70056.

Boon, D; Marchitti, SA; Colonna, KJ; Chowdhury-Paulino, IM; Li, W; Berky, A; Restrepo, C; Jack, M; Goodman, JE. 2025. “A systematic review of nonsugar sweeteners and cancer epidemiology studies.” Adv. Nutr. 16(12):100527. doi: 10.1016/j.advnut.2025.100527.

Li, W; Goodman, JE; Rege, SV; Lewis, RJ; Dinkelacker, BT. 2025. “Risk-of-bias tools in air pollution epidemiology: A commentary.” J. Toxicol. Reg. Pol. 1(2):1-9. doi.: 10.69982/jtrp-25-0006.

Marchitti, SA; Boon, D; Jack, M; Goodman, JE. 2025. “Lack of genotoxic and carcinogenic potential for nonsugar sweeteners: A review of animal and mechanistic evidence.” Adv. Nutr. 16(12):100552. doi.: 10.1016/j.advnut.2025.100552.

Upcoming Presentations

 

Society of Toxicology (SOT) 65th Annual Meeting and ToxExpo. March 22-25, 2026. San Diego, CA.

  • “An Epidemiologic Evaluation of Inorganic Arsenic Exposure and Teratogenic Effects.” K. Colonna, S. Boomhower.
  • “An Evaluation of the Epidemiologic and Experimental Animal Evidence of Oral Cadmium Exposure and Teratogenic Effects.” P. Andrew, J. Chien, K. Colonna, S. Boomhower.
  • “Exercises in Applying Chemical Class Skin Sensitization Hazard Determinations.” S. Larch, T. Dugan, R. Ticknor, I. Hadley, I. Mohar, T. Lewandowski.
  • “Prevalence and Toxicity Evaluation of the Types of PFAS Found in Medical Device Extractables and Leachables Datasets.” B. Cronin, M. Matsushita, M. Knapp, R. Chang, J. Zhang.
  • “Considerations for Appropriate Application of One-Compartment Toxicokinetic Models to Assess Per- and Polyfluoroalkyl Substances (PFAS) Exposures.” J. Chien, R. Rogers, B. Beck.
  • “Survey of Neurotoxicants Released from Medical Devices.” M. Khazaee, E. Kaye, J. Cohen.
  • “Identification of Chemicals of Endocrine and Reproductive Concern in Medical Device Extractables and Leachables Datasets.” C. Meakin, L. Borton.
  • “Comparative Review of Carcinogenicity Testing Guidelines in Context of Medical Device Risk Assessment.” R. Chang, M. Khazaee, J. Goodman.
  • “Hazard Evaluation and Structural Analysis of Organophosphorus in Medical Device Extractables and Leachables Datasets.” M. Matsushita, B. Cronin, H. Gadol, R. Chang.
  • “Determination of a Medical Device Parenteral Non-cancer TTC Based on In Silico ADME.” T. Builee (Solventum), M. Peterson, S. Bond (Jordi Lab), R. Bachorz (Simulations Plus, Inc.), V. Lukacova (Simulations Plus, Inc.), V. Levelut (NAMSA), M. Hahn (Eurofins Medical Device Services).
  • “Case Study of Permissible Daily Exposure Limit Derivation for Butyl Oligomer (C21H40): Gradient vs. ICH Q3E.” I. Mohar, I. Hadley.
  • “Integrating Total Organic Carbon (TOC) Analysis into Chemical Characterization for Toxicological Risk Assessment: A Case Study Evaluating the Relationship Between TOC and Gravimetric Residues.” S. Kearing, C. Meakin, L. Borton.
  • “Case Studies Evaluating Neonatal Susceptibility to Chemical Exposures from Medical Devices and Implications for Toxicological Risk.” Workshop. J. Cohen.
  • “Product Stewardship “Speed Round”: Latest Updates on Proposition 65, PFAS, Microplastics, and More.” Exhibitor-Hosted Session. T. Lewandowski, M. Peterson, J. Zhang.

Semiconductor Environmental Safety and Health Association (SESHA) 48th Annual Symposium. April 13-16, 2026. Tempe, AZ.

  • “Using New Approach Methods (NAMs) for Chemical Risk Assessment.” J. Kneeland, C. Butler, A. Lewis.

Previously Presented

 

American College of Toxicology (ACT) 2025 Annual Meeting. November 16-19, 2025. Phoenix, AZ.

  • “A Risk-Based Material Characterization Framework for Shelf-Life and Change Management in Medical Devices.” D. Diaz-Diestra, A. Gauthier.
  • “ICH S1B(R1) WoE for Next-Generation Multi-Target GLP-1 Therapies: Do We Still Need the Two-Year Rat Bioassay?” A. Gauthier, K. Roach, M. Khazaee, I. Mohar.
  • “Umbrella Review of Randomized Controlled Trial Evidence on GLP-1RA Treatment and Risk of Thyroid and Pancreatic Cancers.” M. Khazaee, D. Boon, K. Roach, A. Gauthier, I. Mohar.

Society for Risk Analysis (SRA) Annual Meeting. December 7-10, 2025. Washington, DC.

  • “An Evaluation of Intermittent Lead Exposure in Children and Adults Using US EPA Blood Lead Models.” K. Colonna, R. Mattuck, S. Boomhower.
  • “How Bias Impacts the Interpretation of Talc and Cancer Epidemiology Study Results.” J. Goodman, K. Colonna, D. Boon.

American Geophysical Union (AGU) 25. December 15-19, 2025. New Orleans, LA.

  • “Investigating Gas-Particle Partitioning of PFAS and Its Atmospheric Implications.” A. Hrdina, N. Afshar-Mohejar, C. DesAutels.

By the Way… 

 

According to an article published in The Lancet, data shows that, while the commonly cited 10,000 daily steps may be a useful goal for more active individuals, covering 7,000 steps per day is associated with “clinically meaningful improvements in health outcomes.”

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