The Globally Harmonised System of Classification and Labelling Chemicals (GHS) is a hazard identification and communication framework with worldwide implementation. Its widespread and growing adoption has shaped the landscape of chemical compliance and provided the foundation for product stewardship and green chemistry programs. As a result, accurate and consistent identification of hazards is increasingly important to regulators, companies throughout the supply chain, and the public. Gradient recognizes the complexities of GHS, both with respect to technical attributes of the framework and the challenges that come from implementing GHS requirements in a global economy. We complement our familiarity with the GHS framework with in-depth expertise in toxicology, ecotoxicology, and chemistry. Together, these skills are critical for meeting basic GHS-related requirements, particularly when evaluating complex or novel chemicals with limited data or toxicity information.
Gradient Expertise:
Global Hazard Assessment and Compliance Support
Gradient conducted hazard assessments of a portfolio of more than 1,600 chemicals for a global oil and gas company. We used these hazard assessments to understand product-level hazards, update US and international Safety Data Sheets (SDSs) to meet Globally Harmonised System of Classification and Labelling Chemicals (GHS) criteria, and develop a comprehensive database. Our hazard assessments and database are an integral part of our client’s long-term product compliance sustainability plan.
Globally Harmonised System of Classification and Labelling Chemicals (GHS) Technical Report for Copper
Gradient authored a technical report detailing the scientific basis for the hazard classification of different forms of copper metal according to the Globally Harmonised System of Classification and Labelling Chemicals (GHS) framework and the European Commission’s Classification, Labelling and Packaging of Substances and Mixtures (CLP). With a focus on particle size and bioaccessibility, we evaluated and summarized existing scientific literature on human and ecological health effects and prepared this comprehensive report to serve as a public-facing communication tool.
Multi-Jurisdictional Support for Automotive Manufacturer
To support expansion into new markets, Gradient reviewed and summarized country-specific regulations and requirements related to chemical compliance, including Globally Harmonised System of Classification and Labelling Chemicals (GHS) adoption, Safety Data Sheets (SDSs), chemical registration/notification, and consumer labels. Subsequently, Gradient determined the data needs and facilitated the completion of various compliance-related tasks for multiple countries.
Ongoing Toxicology Support for Hazard Assessment of New Chemicals
Gradient conducted new material reviews for a printer equipment and ink company, which involved a Globally Harmonised System of Classification and Labelling Chemicals (GHS) hazard assessment for each new chemical introduced into the market. The client used these assessments to create compliant Safety Data Sheets (SDSs) around the globe, as well as benchmark products against an internal product stewardship standard.
