Fall 2025

What’s New at Gradient

Awards and Announcements

 

Lisa Bailey has been accepted as a Fellow of the Academy of Toxicological Sciences (ATS).

Matthew Mayo has been certified as an Environmental Manager (CEM) by the Nevada Division of Environmental Protection.

Nicole Olgun will teach “Introduction to Toxicology,” an online course, for the 2025-2026 academic year at St. John’s University.

Publications

 

Borton, L; Coleman, K. 2025. “Material-mediated pyrogens in medical devices: Myth or reality?” ALTEX – Altern. Anim. Ex. doi: 10.14573/altex.2504231.

Builee, T; Kennedy, T; Levelut, V; Hahn, M; Bond, S; Peterson, MK; Hsia, FK; Stornetta, A; Erickson, K; Ehman, KD; Prabhakar, B; Bagley, B; Parker, S. 2025. “Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern values.” Front. Toxicol. 7. doi:10.3389/ftox.2025.1600127.

Burns, ES; Olgun, NS; Friend, SA; McKinney, WG; Sinsel, EW; Reynolds, JS; Leonard, SS. 2025. “Peracetic acid effects on human bronchial epithelial cells in an air liquid interface.” PLoS One. 20(5):e0322926. doi: 10.1371/journal.pone.0322926.

Goodman, JE; Boon, DN; Prueitt, RL. 2025. “Talc, ovarian cancer, and recall bias in the sister study.” Glob. Epidemiol. 9:100203. doi: 10.1016/j.gloepi.2025.100203.

Goodman, JE; Drury, NL; Marchitti, SA. 2025. “Comment on ‘IARC Workshop on the Key Characteristics of Carcinogens: Assessment of End Points for Evaluating Mechanistic Evidence of Carcinogenic Hazards.'” Environ. Health Perspect. doi: 10.1289/EHP17383.

Goodman, JE; Korchevskiy, A; Wylie, AG. 2025. “Comparison of various methodological approaches to model asbestos thresholds for mesothelioma.” Front. Public Health 13. doi: 10.3389/fpubh.2025.1569343.

Goodman, JE; Rhomberg, LR; Cohen, SM; Mundt, KA; Case, B; Burstyn, I; Becich, MJ; Gibbs, G. 2025. “Challenges in defining thresholds for health effects: Some considerations for asbestos and silica.” Front. Epidemiol. 5. doi: 10.3389/fepid.2025.1557023.

Govindarajan, A; Rifai, HS; Nguyen, M. 2025. “Modeling water column dynamics in an urban estuary and their impacts on pollutant transport and system behavior.” Environ. Sci. Pollut. Res. 32:8959-8974. doi: 10.1007/s11356-025-36258-x.

Kuhn, BK; Vrugt, B; Low, A; Goodman, JE; Attanoos, R. “Comparative analysis of asbestos body and fiber content in formalin-fixed vs. paraffin-embedded lung tissue.” Front. Public Health 13. doi: 10.3389/fpubh.2025.1590802.

Longo, WM; Sinha, S; Imagawa, M; Arnold, WA; Hatton, J; Pennell, KD; Simcik, MF. 2025. “In situ sequestration of per- and polyfluoroalkyl substances in aquifer materials using polydiallyldimethyl ammonium chloride-stabilized powdered activated carbon.” Environ. Sci.: Water Res. Technol. 11(6):1527-1541. doi: 10.1039/D4EW00752B.

Upcoming Presentations

 

EUROTOX 2025. September 14-17, 2025. Athens, Greece.

  • “Evaluation of US EPA’s TSCA Rule for the Occupational Use of Carbon Tetrachloride and Proposal for a Revised Occupational Exposure Value.” S. Marchitti, L. Bailey.
  • “Non-sugar Sweeteners and Cancer – Integrating Results of a Systematic Review of Epidemiology Studies with Toxicology Evidence.” D. Boon, S. Marchitti, K. Colonna, I. Chowdhury-Paulino, W. Li, A. Berky (Geosyntec), C. Restrepo, M. Jack (American Beverage Association), J. Goodman.

2025 American Center for Life Cycle Assessment (ACLCA) Conference. September 15-18, 2025. Atlanta, GA.

  • “A Comparative Life Cycle Assessment of Corrective Action Alternatives to Evaluate Sustainable Remediation.” Q. Zhang, M. Biega, A. Lewis.

PSX 2025. September 16-18, 2025. Houston, TX.

  • “Lessons Learned in Conducting California’s Safer Consumer Products Alternatives Analysis.” T. Lewandowski, J. Zhang.
  • “Plastic Nano- and Microparticles: Health Effects and Mechanisms of Toxicity.” M. Tymchak, M. Peterson, A. Yeh (Dow Chemical Company).
  • “Navigating Consumer Product PFAS Regulations Across State Lines: Practical Strategies for Product Stewards.” J. Zhang, K. Reynolds Reid, S. Zhao.

Northeast Sustainable Communities Workshop (NSCW) 2025. September 17-18, 2025. Schenectady, NY.

  • “Not Your Grandmother’s EJ.” N. Slagowski (panelist).

Society for Chemical Hazard Communication (SCHC) 2025 Annual Meeting. September 20-25, 2025. Washington, DC.

  • “California Proposition 65 Updates and Emerging Issues: What Lies Ahead?” K. Reid.
  • “Hazard Classification Best Practices to Support a Sustainable Chemical Portfolio.” A. Lewis.

Association for Environmental Health and Soils (AEHS) 41st Annual International (East Coast) Conference on Soils, Sediments, Water, and Energy. October 20-23, 2025. Amherst, NY.

  • “Household Products as a Potential Source of Microplastics Contamination in Domestic Wastewater.” R. Hebert, K. Zic, P. Clyde, D. Kleinberg, J. Kneeland.

Air & Waste Management Association (A&WMA) Lake Michigan States Section (LMSS) 2025 Annual Air Conference. October 21, 2025. Oakbrook Terrace, IL.

  • “PFAS in Air.” C. DesAutels (panelist)

Orthopaedic Surgical Manufacturers Association (OSMA) 2025 Fall Meeting. October 22-23, 2025. Rockville, MD.

  • “When Change is the Only Constant: Updates to ISO 10993-1 and Other Hot Topics in Biocompatibility.” L. Borton.

PharmaEd Extractables and Leachables Summit West 2025. November 4-5, 2025. La Jolla, CA.

  • “An Overview of Polyfluoroalkyl Substance (PFAS) Toxicology, Regulation, and Biocompatibility.” I. Mohar.

American Association of Pharmaceutical Scientists (AAPS) 2025 PharmSci 360. November 9-12, 2025. San Antonio, TX.

  • “Next-Generation Incretin Therapies: Approaches to Carcinogenicity Safety Assessment.” A. Gauthier.

Society of Environmental Toxicology and Chemistry (SETAC) North America 46th Annual Meeting. November 16-20, 2025. Portland, OR.

  • “Challenges and New Approaches in Conducting Alternatives Assessment for 6PPD in Motor Vehicle Tires.” J. Zhang, T. Manidis, T. Dugan, T. Lewandowski.
  • “Human Heath, Environmental, Physicochemical, and Regulatory Information for Amine Solvents, Degradation Products, and Impurities Associated with Post-Combustion CO2 Capture: A Screening Assessment.” T. Manidis, J. Chien.
  • “Sediment Dating in Environmental Investigations: A Review.” J. Kneeland.

2025 Society for Risk Analysis (SRA) Annual Meeting. December 7-11, 2025. Washington, DC.

  • “Next-Generation Incretin Therapies: Approaches to Carcinogenicity Safety Assessment.” A. Gauthier.

Previously Presented

 

2025 Prop. 65 Annual Conference. September 8, 2025. San Francisco, CA.

  • “Safe Harbor Levels and Exposure Assessments: Best Practices in Assessing Prop. 65 Compliance.” S. Boomhower (panelist).

North American Science Associates (NAMSA) North American Biocompatibility Summit (NABS) 2025. September 10, 2025. Minneapolis, MN.

  • “Material-Mediated Pyrogens in Medical Devices: Myth or Reality?” L. Borton, K. Coleman (Medtronic).
  • “Risk-Based Framework for Evaluating Toxicological Potentiation Between Structurally Diverse Non-grouped Extractables.” A. Gauthier, K. Roach.
  • “What Value Does Total Organic Carbon (TOC) Analysis Provide to Chemical Characterization Data?” S. Kearing, C. Meakin.

By the Way… 

 

“For the first time in more than a decade, obesity dipped slightly in American adults in 2024.  A study in the Journal of the American Medical Association (JAMA) Health Forum found and theorized that this decrease may be due to a rise in GLP-1 weight loss drug usage.”

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